RexoFace: The Next Generation of Skin Rejuvenation Has Arrived in Guildford
As an aesthetic nurse practitioner, I continually evaluate new treatments to ensure I offer my patients the most effective, evidence-based options available. That's why I'm excited to introduce RexoFace to my clinic — a treatment that represents a genuine advancement in skin rejuvenation.
What is RexoFace?
RexoFace is a Swiss-made biostimulator that uses Exobiotic® technology — a patented system that extracts extracellular vesicles (EVs) from probiotic bacteria. These tiny particles, just 20-200 nanometres in size, are nature's communication system between cells.
Unlike traditional skin boosters that primarily add hydration, RexoFace works at the cellular level to stimulate your skin's regenerative processes. Each treatment contains 20 billion lyophilised (freeze-dried) particles that, when applied via microneedling, can penetrate the skin barrier and communicate directly with your fibroblasts — the cells responsible for producing collagen and elastin.
The Science: What Does the Research Say?
The technology behind RexoFace is supported by more than 20 clinical studies. Research published in peer-reviewed journals has demonstrated that extracellular vesicles derived from lactic acid bacteria can:
Stimulate fibroblast proliferation and collagen synthesis — A 2023 study in the journal Cells showed that probiotic-derived EVs increased collagen production comparable to retinoic acid, the gold standard anti-ageing compound.
Reduce inflammatory markers — Research demonstrates that these EVs can decrease matrix metalloproteinases (MMPs), the enzymes that break down collagen, and reduce inflammatory cytokines such as IL-6 and IL-8.
Support wound healing — Studies show enhanced tissue regeneration, new blood vessel formation, and accelerated healing.
Who is RexoFace Suitable For?
RexoFace may be particularly beneficial for patients concerned with:
• Early signs of ageing and loss of skin quality
• Fine lines and textural changes
• Dull, tired-looking skin
• Uneven skin tone or mild pigmentation
• Acne scarring
• Maintaining results from other aesthetic treatments
Book Your Consultation
If you'd like to learn more about whether RexoFace could help you achieve your skin goals, I'd be happy to discuss this during a consultation. We'll review your skin concerns, medical history, and create a personalised treatment plan.
RexoFace with Microneedling: £400 | RexoFace Add-on: £250
Ready to Embrace a Fresher You?
Contact Verse Medical Aesthetics in Guildford to book your anti-wrinkle consultation today.
📍 Verse Medical Aesthetics — Guildford, Surrey
📞 +44 7476 695696 📧
marta@versemedicalaesthetics.com
Just 3 minutes from Guildford Station, Verse Medical Aesthetics offers expert-led skin treatments with real results and zero stress.
What's in the Formula?
RexoFace combines the Exobiotic® particles with a powerful diluent containing:
PDRN (Polydeoxyribonucleotides) — DNA fragments that activate the adenosine A2A receptor, promoting tissue regeneration, angiogenesis, and anti-inflammatory effects. A meta-analysis of clinical trials confirms PDRN's role in enhancing wound healing and skin rejuvenation.
Niacinamide — Research shows this vitamin B3 derivative increases collagen production, reduces MMPs, and improves skin barrier function.
Tranexamic Acid — Clinical studies demonstrate its effectiveness in reducing pigmentation by inhibiting melanin production and decreasing vascular factors that contribute to melasma.
Alpha-Arbutin — A tyrosinase inhibitor that safely reduces melanin production for more even skin tone.
Vitamin C — An antioxidant essential for collagen synthesis.
Glutathione — The body's master antioxidant, with research showing benefits for skin brightening.
Two types of hyaluronic acid, 13 amino acids, and 5 skin peptides complete the formula.
Why I Chose RexoFace
Three factors convinced me this treatment deserves a place in my clinic:
1. Refrigerated storage — RexoFace is kept at 4-8°C, which preserves the biological activity of the active ingredients. This is unusual in aesthetic treatments and indicates a commitment to product integrity.
2. Lyophilised formulation — The freeze-dried powder is reconstituted just before treatment, ensuring maximum potency. This is the same preservation method used for vaccines and biologics.
3. Evidence-based approach — The combination of probiotic-derived EVs with proven actives like PDRN represents a sophisticated, multi-target approach to skin rejuvenation.
What to Expect After The Rexoface
RexoFace is applied via microneedling, which creates tiny channels in the skin for optimal product delivery. The treatment takes approximately 45-60 minutes. You may experience mild redness for 24-48 hours, similar to standard microneedling.
I recommend a course of 3-4 treatments spaced 2-4 weeks apart for optimal results, with maintenance treatments every 3-6 months.

