Profhilo vs Fillers: What’s the Difference?
A guide to choosing the right injectable for your skin, support, and structure.
If you’ve been scrolling through Instagram or chatting with friends about skin boosters, you’ve probably come across both Profhilo and dermal fillers. But what exactly do they do—and which one is right for you?
Let’s break it down.
💧 What is Profhilo?
Profhilo is often called an “injectable moisturiser”—but it’s so much more than that.
It contains pure hyaluronic acid (HA) just like fillers, but instead of plumping one area, it spreads through the skin and stimulates your natural collagen and elastin.
💡 Think of it like a full-face skin reviver—perfect for:
Crepey texture
Fine lines
Dull, tired skin
Loss of firmness
You get a subtle, all-over glow and tightening effect after just two sessions, spaced a month apart.
💉 What about dermal fillers?
Fillers are typically crosslinked HA, injected to restore volume or enhance features.
They’re ideal for:
Sculpting cheeks or jawlines
Softening deep folds (like nasolabial lines)
Lip enhancement
But because they stay where they’re injected, they don’t improve skin quality across the face like Profhilo.
🧬 Not All HA Injectables Are the Same
In our clinic, we use three distinct types of HA-based injectables: Profhilo, Profhilo Structura, and dermal fillers like RHA® and Restylane®.
Each has a unique composition, texture, and purpose. Here’s how they compare:
| Property | Profhilo | Structura | RHA / Restylane Fillers |
|---|---|---|---|
| HA Content | 64mg per 2ml | 45mg per 1.1ml | 15–25mg/ml (varies by product) |
| Crosslinking | None (thermally bonded) | Light cross-linked | RHA®: Light Restylane: Light–Heavy |
| Consistency | Very fluid, spreads easily | Soft, smooth | Gel-like, varies by brand |
| Injection Depth | Superficial subcutaneous (BAP) | Deep subdermal or supraperiosteal | Varies — superficial to deep (e.g. bone) |
| Main Action | Hydration, glow, collagen/elastin | Support, elasticity, tissue stimulation | Volume, contour, shaping |
| Best For | Crepey skin, dullness, mild laxity | Soft lift, post-weight loss, tissue fatigue | Cheeks, lips, jawline, deep folds |
| Duration | ~6 months | ~6–9 months | 6–12 months |
| Biostimulatory Effect | Yes — collagen + elastin | Yes — structural support + stimulation | No direct stimulation — structural only |
✨ Glow · Support · Shape — The Verse Approach
At Verse Medical Aesthetics, we take a Glow · Support · Shape approach to facial rejuvenation:
Glow with Profhilo — to hydrate, firm, and restore radiance
Support with Profhilo Structura — to gently lift and support tissue from within
Shape with RHA® / Restylane® — to define contours and restore lost volume
This layered method works with your facial anatomy and enhances your features without overfilling. It’s ideal for those who want to look like themselves, just fresher, firmer, and naturally glowing.
💬 Still not sure what’s right for you?
That’s exactly what consultations are for. We’ll assess your skin, goals, and comfort level, and create a tailored plan using the products that best suit your features, not someone else’s.
📩 Tap the button below to book a consultation.